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Some practical considerations when to use iTBS and 10 Hz rTMS for depression treatment

A recent systematic meta-analysis study by Shen and Fang (August 2024) published in the British Journal of Hospital Medicine ( https://www.magonlinelibrary.com/doi/full/10.12968/hmed.2024.0157 ) shows comparable efficacy (remission or response rate) and safety of iTBS and rTMS treatment for patients with depression and both treatment protocols significantly better than sham treatment. But a nuanced understanding is important for clinical application and personalised TMS treatment for depression. It is possible that one protocol might be better over another protocol for some individuals. In this context, Slan et al. (August 2024 : https://doi.org/10.1016/j.jad.2024.08.129) published research in the Journal of Affective Disorders is worthy of consideration. In their retrospective naturalist treatment study based on 414 patients they show that iTBS was less efficacious in males than females and 10 Hz rTMS was more efficacious in patients over the age of 50.

In summary:

Generally both the iTBS and 10 Hz rTMS have comparable efficacy
10 Hz rTMS protocol should be preferred for females and patients over 50 years of age.

Figure below from Slan et al. (2024)

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4.9

O L

21:49 19 Apr 25

I would highly recommend Oxford Brain and Mind to any person seeking help with any psychiatric issue and assessments for autism. I tried my luck in contacting the clinic on 2 Jan (a day after the new year / public holidays when most clinics were closed). I was desperate to get help for someone I love for anxiety/depression-related issues. Sanjay was very responsive and understanding, securing a slot for us to see Dr Malhotra quickly. Dr Malhotra was thorough in her assessment and diagnosis, offering an effective treatment plan. The plan works perfectly well for us. The plan included CBT with Wendy who is very helpful in imparting important skills. The plan also included an assessment for autism. Dr Malhotra and Sanjay are both professional and kind in their approach and in conducting the lengthy assessments. We appreciate their help very much.

Response from the owner 07:06 20 Apr 25

Dear O L, Thank you so much for your kind review! We are pleased to hear that your experience with Oxford Brain and Mind has been positive. We are also pleased to hear that Dr Malhotra’s thorough assessment and effective management plan worked well for you. Thank you again for recommending Oxford Brain and Mind.

Ben K.

16:42 03 Apr 25

I saw Dr Saïk de La Motte de Broöns de Vauvert for an assessment. It was very comprehensive and considered many complicating factors. Overall very positive and following assessment I felt my concerns were well looked after and that the doctor offered to go to lengths to secure a prescription. The location is very clean and nicely decorated too.

Response from the owner 18:15 03 Apr 25

Thank you Ben for your positive review for Oxford Brain and Mind. We are glad that you had an excellent experience with Dr de La Motte and the clinic.

Romy C.

11:37 06 Feb 25

I am so grateful for Dr Malhotra’s kindness and compassion, which is sadly not something I have often experienced in my mental healthcare. I really felt heard and respected. I am also impressed by her insight into my very complex, decades long mental illness. In just two long sessions she was able to offer me a new perspective on my condition and to make sense of many things. She provided me with comprehensive diagnostic assessment that will be so helpful going forward. I also now feel better equipped to make decisions about my future treatment.Thanks also to Sanjay at Oxford Brain and Mind for dealing so efficiently and sensitively with the administrative side of things.

Response from the owner 09:42 07 Feb 25

Dear RomyWe are pleased to hear that your experience with Dr Malhotra was so positive. It’s wonderful to know that you felt heard, respected, and understood throughout your assessment process.Oxford Brain and Mind is proud to be led by Dr Malhotra. Her expertise, compassion, and dedication to her patients are truly commendable. We are also pleased that Sanjay was able to provide you with efficient and sensitive administrative support.We strive to provide the highest quality of care to all of our patients, and your feedback is invaluable in helping us achieve this goal.Warm regards,Oxford Brain and Mind

Leo C.

14:01 17 Dec 24

Great experience

Response from the owner 14:25 17 Dec 24

Thank you Leo for your feedback.

Livi G.

09:36 03 Dec 24

Excellent practice – highly recommended. Sanjay was extremely accommodating in helping me secure an appointment last minute. Super responsive communication and easy to reach. Dr Saik made me feel very at ease and was incredibly helpful with my treatment, I will definitely be arranging a follow up. Overall, very grateful for the support and care I received here.

Response from the owner 10:12 03 Dec 24

Thank you Livi for your kind words. Our colleagues value your feedback.

Naomi W.

10:10 02 Dec 24

Sanjay and the team were very thoughtful and kind in their assessment and treatment. Would highly recommend Oxford Brain and Mind.

Response from the owner 10:29 02 Dec 24

Thank you so much Naomi for your kind words.

Laura V.

17:12 22 Nov 24

Our experience with Oxford Brain and Mind was thoroughly positive. The staff were informative, kind and supportive!

Response from the owner 21:13 22 Nov 24

Thank you so much Laura for your positive review. Much appreciated.

Daniel R.

11:11 06 Oct 24

Absolutely fantastic experience! I recently had an ADHD assessment at this clinic, and I couldn’t be happier with how it went. From the moment I walked in, I felt welcomed and at ease. The staff were friendly, professional, and really took the time to understand my concerns.The assessment itself was thorough but felt relaxed – the clinician made sure I understood each step and answered all my questions. I never felt rushed, and they genuinely listened to everything I had to say, which was such a relief. By the end, I felt like I finally had some clarity and a clear plan for what to do next.The whole process was smooth, and booking was a breeze too. If you’re considering an ADHD assessment or any kind of support, I highly recommend this clinic. They really know their stuff and made what could have been a stressful experience into a very positive one.

Response from the owner 12:38 06 Oct 24

Thank you Daniel for your lovey feedback. We appreciate your feedback for our clinicians as well as for the clinic as a whole. We are really pleased to hear that you had a very positive experience with us.

Genevieve B.

16:55 23 Jan 24

I highly recommend Dr Malhotra. She is warm and patient, creating a comfortable and supportive environment. She performed a thorough diagnosis that I have not been able to experience in the past. The clinic is welcoming, and communication for scheduling and follow-ups is always prompt and efficient. My experience has been very positive.

Response from the owner 11:15 24 Jan 24

Thank you Genevieve for your positive feedback for our clinic Oxford Brain and Mind and Dr Malhotra. We very much appreciate it.

Julia M.

19:06 30 Dec 23

Response from the owner 19:50 30 Dec 23

Thank you Julia for your 5* review.

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